123P Associations between N-cadherin (N-cad) as an epithelial-mesenchymal transition (EMT) marker and androgen (AR) and estrogen receptors (ER) expression in prostate cancer (PCa)

Abstract

EMT is an important mechanism of cancer progression and its regulation is crucial to understand for better treatment strategies. Androgens and estrogens are known regulators of PCa. The role of their receptors (AR, ERα, ERβ) in regulating EMT in PCa is still controversial. The aim was to assess possible links between levels of those receptors and N-cad as an EMT marker in PCa.