Abstract
It is well known that tunneling nanotubes (TNT) are dynamic, actin-based, cytoplasmic bridges formed between donor and acceptor cell through which variety of cargos and signals can be transported. Their main functional role is cell-to-cell communication, but several studies point out that TNTs arise to protect cells, as a response to stress. The presence of TNTs as cellular network correlates with diverse stress factors such as hypoxia, hydrogen peroxide exposure, serum starvation, inflammation.
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