123 Anti-BP180, Pruritus, and Thymus and Activation-Regulated Chemokines as Surrogate Markers for Disease Activity in Bullous Pemphigoid

Abstract

Bullous pemphigoid disease activity index (BPDAI) is the standard indicator of disease activity in bullous pemphigoid (BP). However, examining patients’ whole body is burdensome to both the patient and health care workers and is subjected to inter-examiner bias, hence the need to investigate other surrogate markers for BPDAI. The purpose of the study is to quantify and correlate candidate surrogate disease markers of BP namely visual analogue scale for pruritus (VAS-pruritus), thymus and activation-regulated chemokines (TARC), and anti-BP180 to bullous pemphigoid disease activity index (BPDAI).