Abstract
TβR2 is a ligand-binding receptor for transforming growth factor β – a major regulator of epithelial-mesenchymal transition (EMT). EMT can be defined in cancers by the expression of several markers, E- and N-cadherins being ones of the most widely used. Previously we have shown that N-cad neoexpression can be considered a better EMT marker than E-cadherin downregulation, so N-cad was used as a surrogate of EMT. The aim was to study associations of expression of TβR2 as an EMT regulating molecule and EMT marker in PCa.
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