Abstract

The widespread use of oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX) in advanced gastric cancers is mainly based on clinical trials conducted at Western/European countries. The prospective data on efficacy and safety of FOLFOX in advanced gastric cancer is lacking from the developing countries. In this prospective observational study, we evaluated the efficacy and toxicity of mFOLFOX-6 in patients with advanced gastric or gastro-esophageal junction (GEJ) adenocarcinomas, as first-line palliative chemotherapy.

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