1222P Spontaneous ventilation video-assisted thoracoscopic surgery for geriatric patients with non-small cell lung cancer: A propensity score matching analysis

Abstract

The feasibility and safety of spontaneous ventilation video-assisted thoracoscopic surgery (SV-VATS) in geriatric patients aged ≥60 years with non-small-cell lung cancer (NSCLC) remain unclear. A total of 164 geriatric patients with NSCLC undergoing SV-VATS and 1238 patients undergoing mechanical ventilation video-assisted thoracoscopic surgery (MV-VATS) between April 2012 and July 2018 were analysed. We used propensity score matching (PSM) to minimize the difference in baseline characteristics. The perioperative outcomes between the SV-VATS group and MV-VATS group were compared. After PSM, 152 of 164 patients in the SV-VATS group, and 152 of 1238 patients in the MV-VATS group were matched based on similar propensity scores. There were no significant differences in anesthesia time (225 ± 94 vs 235 ± 62 min; P =0.30), surgery time (191 ± 105 vs 177 ± 80 min; P =0.24) and intraoperative bleeding (75 ± 217 vs 62 ± 120 ml; P =0.72) between two groups. After surgery, hospitalization (17 ± 7 vs 16 ± 7 days; P =0.30), chest tube duration (6 ± 9 vs 4 ± 2 days; P =0.366) and incidence of complications (7% vs 10%; P =0.41) were non-significant and comparable between both groups. In this study, SV-VATS proved to be feasible and safe in the geriatric patients with NSCLC. Further investigation is required to evaluate the long-term effects of SV-VATS in geriatric patients with NSCLC.