1214 ONCOLOGICAL OUTCOMES IN LOW, INTERMEDIATE AND HIGH D'AMICO RISK PATIENTS UNDERGOING LAPAROSCOPIC RADICAL PROSTATECTOMY AT A SINGLE UK CENTRE

Abstract

You have accessJournal of UrologyProstate Cancer: Localized1 Apr 20131214 ONCOLOGICAL OUTCOMES IN LOW, INTERMEDIATE AND HIGH D'AMICO RISK PATIENTS UNDERGOING LAPAROSCOPIC RADICAL PROSTATECTOMY AT A SINGLE UK CENTRE Andrew Moon, Nikhil Vasdev, Rajan veeratterapillay, Mark Johnson, Anna O'Riordan, and Naeem Soomro Andrew MoonAndrew Moon Newcastle upon Tyne, United Kingdom More articles by this author , Nikhil VasdevNikhil Vasdev Newcastle upon Tyne, United Kingdom More articles by this author , Rajan veeratterapillayRajan veeratterapillay Newcastle upon Tyne, United Kingdom More articles by this author , Mark JohnsonMark Johnson Newcastle upon Tyne, United Kingdom More articles by this author , Anna O'RiordanAnna O'Riordan Newcastle upon Tyne, United Kingdom More articles by this author , and Naeem SoomroNaeem Soomro Newcastle upon Tyne, United Kingdom More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2568AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Laparoscopic radical prostatectomy (LRP) is an established treatment option for patients with prostate cancer in selected centres with appropriate expertise. The goal of LRP is to achieve excellent cancer control whilst attempting to preserve normal urinary continence and erectile function. We studied our single centre experience evaluating the oncological outcomes in patients undergoing LRP. METHODS Three hundred and six patient underwent LRP between 2005 and 2011. Patients were divided into D'Amico low, intermediate and high risk groups. RESULTS The mean age was 61.9 years (range 46 – 74 y). The two most important factors predictive of positive surgical margins at LRP were the initial PSA level and tumour stage at diagnosis. The overall PSM rate was 26.7%. For low D'Amico risk patients, the PSM was 24.5%, intermediate risk patients had a PSM of 32.4%, while high risk patients had a PSM of 13.6%. 6.4% of patients sampled had evidence of lymph node positive disease. 5 year PSA progression free survival rates were 83% in low risk patients, 57% in intermediate risk and 41% in high risk. CONCLUSIONS LRP offers good oncological outcomes in the low and intermediate risk groups with low incidence of biochemical recurrence for patients with localised disease. Our high risk group has a low incidence of PSM and a 5 year PSA progression free survival rate of 41%. Patients with high risk, but non-metastatic, prostate cancer can be offered a minimally invasive prostatectomy in an experienced centre. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e497 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Andrew Moon Newcastle upon Tyne, United Kingdom More articles by this author Nikhil Vasdev Newcastle upon Tyne, United Kingdom More articles by this author Rajan veeratterapillay Newcastle upon Tyne, United Kingdom More articles by this author Mark Johnson Newcastle upon Tyne, United Kingdom More articles by this author Anna O'Riordan Newcastle upon Tyne, United Kingdom More articles by this author Naeem Soomro Newcastle upon Tyne, United Kingdom More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...