1204 Enhancing NK cell function in the ‘cold’ tumor microenvironment of prostate cancer with a novel tri-specific Killer Engager against prostate-specific membrane antigen (PSMA)

Abstract

BackgroundNatural killer (NK) cell effector function is suppressed in the tumor microenvironment (TME) of metastatic castration-resistant prostate cancer (mCRPC), the lethal form of prostate cancer. This is largely due to...