Abstract
Introduction: International decision-making bodies recommend the integration of Patient Reported Outcome Measures (PROMs) alongside standardised clinical outcomes. Methodology evaluating PROMs after types of breast reconstruction (BRR) has been poor with respect to study design, statistics, missing data and absence of prospective documentation of pre-defined complication data in a systematic review of all studies since 19781. Few studies investigate the clinical meaning and magnitude of HRQL changes following types of immediate latissimus dorsi (LD) BRR (either implant-assisted (LDI) or tissue only autologous (ALD)) in relation to effective covariates such as clinico-pathological factors, graded complications and adjuvant treatments.
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