Abstract

Blood pressure(BP) response to exercise and levels of vasoactive substances are being investigated in normotensive(NBP) children of hypertensive(HBP) parents. Preliminary, but thus far significant, findings in 11 white(W) and 22 black(B) children (10-17 yrs)include: mothers of B children had higher (p<.002) systolic (SBP) and diastolic(DBP) pressures (p<.009) than W mothers. Although resting heart rates were lower in B (103/min) than W (122/min) children (p<.002), there were no differences between resting SBP and DBP in the children. However, at maximum exercise DBP was significantly greater in B (95mmHg) than W (88mmHg) children (p<.03). Vasoactive substance differences are listed below: Racial differences in BP and vasoactive substance measurements have been established in adults with HBP. These data suggest that similar differences already exist in resting heart rates, in exercise BP, and in vasoactive substance measurements in NBP children of B and W HBP parents. (Supported by HL 19870)

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