118 Epidemiology of cervical cancer in the republic of Belarus

Abstract

Introduction In Belarus, Cervical Cancer (CC) is the 7th most common cancer accounting for 5.8% of all new cancer cases. Objectives The aim of the study was to estimate incidence, mortality and survival rate of newly diagnosed CC in Belarus from 2009 to 2018. Methods The data from the Belarusian Cancer Registry were analyzed. Results The estimated age-standardized incidence rate of CC per 100000 female population in Belarus has decreased from 12.8 in 2009 to 11.2 in 2018 (p 0,05). Comparison of two five-year periods (2009–2013 and 2014–2018) showed that rate of locally advanced (III-IV stage) CC increased from 25.9% to 33.9%, as rate of stage I and II decreased by 7% and 16%, respectively. Comparison of 5-year adjusted survival rates between 2013 and 2018 showed no change for CC stage I (92.8%, SE 0.8% and 93.3%, SE 0.9%, respectively), increased by 13.5% for stage II (57.6%, SE 1.6% and 65.4%, SE 1.8%), increased by 9.4% for stage III (40.3%, SE 2.3% and 44.1%, SE 2.1%), and increased by 67% for stage IV ( 9.4%, SE 1.9% and 15.7%, SE 2.2%). Conclusions With improvement in diagnostics and introduction of the pilot projects of CC screening in some regions of the country over the last decade, CC incidence rates in Belarus have decreased by 12.5%, primarily due to decrease in incidence of early stages of CC. While there was no significant decrease in mortality, adjusted survival for advanced CC stages was improved.