Abstract
Receptor-Interacting Serin/Threonin-Protein Kinase 3 (RIPK3) mediates necroptosis, a programmed form of cell death, which elicits the release of intracellular contents (DAMPs) and cytokines. These substances attract and activate anti-tumoral immune cells, rendering necroptosis highly immunogenic. In lung adenocarcinomas (LUAD), RIPK3 is a tumor suppressive aberrational target, which has been shown to induce immune suppression in the tumor microenvironment.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
