1182-P: Low Socioeconomic Status and Pregnancy Outcomes in Women with Type 2 Diabetes

Abstract

Aims: Pregnant women with pre-existing type 2 diabetes have a high rate of social deprivation. Low socioeconomic status (SES) is associated with adverse pregnancy outcomes. Our objective was to assess the association of low SES with adverse pregnancy outcomes in women with type 2 diabetes. Materials and Methods: We conducted an observational cohort study of women in the MiTy trial. Maternal and neonatal outcomes were compared in women with and without low SES. Low SES was described as recent immigration within the previous 5 years, low maternal education or single-parent households. Results: A total of 502 women were included in the MiTy trial. Of the eligible women, 192 (41.60%) met criteria for low SES. Women with low SES had significantly higher HbA1c at 34 weeks gestation (6.18% vs 5.89%, p=<0.01). Low SES was associated with an increase in preterm birth (28.1% vs 19.7%, p=0.05), neonatal hypoglycemia (19% vs 9.8%, p=0.007), and NICU admission >24 hrs (27.2% vs 16.8%, p=0.01). After adjustment for confounders, low SES was associated with an increased risk of an adverse neonatal composite outcome (44.7% vs 31.8%, p=0.007; OR 1.83 (95% CI 1.16-2.92). Of the components of the low SES composite, low maternal education was most strongly associated with the composite neonatal outcome OR 1.71 (95% CI 1.03 - 2.82, p=0.04). Conclusions: In women with type 2 diabetes, low SES was associated with poorer glycemic control and an increased risk of adverse neonatal outcomes. Special attention should be paid to low maternal education as a predictor of adverse outcomes. Disclosure S.Campbell: Speaker's Bureau; Novo Nordisk Canada Inc., HLS Therapeutics Inc. G.Tomlinson: None. D.Feig: Advisory Panel; Novo Nordisk Canada Inc., Speaker's Bureau; Sanofi, Novo Nordisk Canada Inc. Funding Canadian Institutes of Health Research