Abstract
From 1974 to 1992, 65 patients with uterine sarcomas were referred to Instituto Portugues de Oncologia—Porto. All patients were retrospectively staged according to accepted UICC criteria. The distribution by histologic type was the following: Leiomyosarcoma (LMS)—33 patients (50.8%); mullerian mixed mesodermal tumor (MMM)—14 patients (21.5%); endometrial sarcoma (ES)—16 patients (24.6%) and other histologies—2 patients (3.1%). Overall survival at 2 and 5 years was 74% and 58%, respectively. Age at presentation, initial symptoms, parity and associated medical conditions were recorded. Overall survival (OS) and disease-free survival (DFS) were analysed by histologic type, hormonal status, tumor extension and treatment. Tumor extension and hormonal status were the most important factors in predicting survival (P
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