Abstract
Critical pathways are shared between embryogenesis and cancer; but while the first is an organized and well-regulated process, the last is characterized by entropy. Several works have evaluated the potential of the embryonic microenvironment for controlling tumor development, showing that embryonic stem cell conditioned media are able to reduce metastatic phenotype of cancer cells. In this context, we have previously observed that human embryonic mesenchymal lung cells-conditioned medium (hEML-CM) are able to induce differentiation in tumor cells.
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