Abstract

<h3>Introduction/Background*</h3> After minimally invasive surgery gained popularity in gynecology oncology, laparoscopic operations became widespread among oncologic operations, however more studies evaluating safety and morbidity of laparoscopic surgery during the learning period of laparoscopy are needed. <h3>Methodology</h3> A prospective study of 895 consecutive patients diagnosed with clinical stage I endometrial cancer managed between January 2005 and December 2016 in a Department of Gynaecology Oncology in a tertiary center in the Canary Islands. The open surgery group was compared to the minimally invasive surgery group over these years. Both groups were compared for epidemiological and clinical characteristics, surgery outcomes, pathologic findings, hospital stay and intraoperative and postoperative complications. <h3>Result(s)*</h3> There were no differences between both groups in terms of median age, percentage of previous laparotomies and median BMI. Median operating time was longer for the laparoscopic group, although the observed differences were not significant. The estimated blood loss was significantly less for the laparoscopic group. There were no differences in intraoperative complications although postoperative adverse events were significant lower in the laparoscopic group. Hospital stay was significantly longer in the laparotomic arm. There were no significant differences in the percentage of readmissions, reoperations and death related to treatment between both groups. <h3>Conclusion*</h3> Laparoscopic surgery in early-stage endometrial cancer is a safe and effective surgical approach applicable in any center with appropriate training. It is possible to change drastically the surgical management of endometrial cancer thus reducing significantly morbidity: less blood loss, less postoperative adverse events and shorter duration of hospital stays, compared to laparotomic surgery.

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