1155-P: Seasonal Impact on Sleep and Glycemia in Adolescents with Type 1 Diabetes

Abstract

Sleep is a key component in health maintenance. Adolescents often struggle to obtain sufficient sleep, and those with T1D are at increased risk for diabetes-related sleep disruptions and shorter sleep duration. We sought to examine sleep quality and glycemic outcomes between youth aged 11-17 with T1D, comparing summer (free schedule) and fall (school schedule). Twenty youth (mean 13.8 yrs, 65% female, 90% Non-Hispanic White), ten each during summer and fall, participated in an observational study. Participants were age matched due to sleep recommendation variations. Actigraphy data (sleep duration, sleep efficiency, sleep onset latency, wake after sleep onset) and glycemic data from CGM (TIR, time hyperglycemic (>180mg/dL), time hypoglycemic (<70mg/dL)) were collected simultaneously for one week. No significant differences were found between summer and fall participants for demographics or sleep outcomes. Statistically significant differences were found for time hypoglycemic (p=0.034) and mean sensor glucose (p=0.021) and clinically notable differences were seen with higher TIR and lower hyperglycemia during summer. This study highlights that insufficient sleep is obtained in adolescents with T1D, regardless of season, and seasonal differences appear to exist in glycemic measures. Further research is needed to elucidate the extent of these differences and methods to improve both sleep and glycemia throughout the year. Disclosure E.Fivekiller: None. C.Sakamoto: None. A.J.Karami: None. L.J.Meltzer: Consultant; Egetis Therapeutics, Harmony Biosciences. L.Pyle: None. E.C.Cobry: None. Funding JDRF (5-ECR-2022-1179-A-N to E.C.C.)