1118P Angioside: The role of angiogenesis in lung neuroendocrine tumors according to primary tumor location in left or right parenchyma

Abstract

Well-differentiated lung neuroendocrine tumours (NETs), classified as typical (TC) and atypical (AC) carcinoids, are 30% of NETs. Angiogenesis plays an essential role in the development and progression of NETs. In this context, a higher vascular network represents a marker of differentiation, with positive prognostic implications. This phenomenon is called ’neuroendocrine paradox’, with vascularization being inversely related to tumour aggressiveness. No data are available about the role of angiogenesis in left vs right-sided lung NETs.