Abstract
If heparin induced thrombocytopenia (HIT) is strongly suspected, a non-heparin anticoagulant should be started as risk of thrombosis is high; however, this needs to be balanced by unnecessary and potentially fatal bleeding (eg. cardiac tamponade) if HIT is misdiagnosed. A high (eg. optical density OD ≥1.4) ELISA reading is used at our institution to suggest the presence of “true HIT” with a high concentration of platelet activating antibodies. Many institutions do not have access to rapid ELISA results, thus knowing which pre-, intra-, and post-operative factors are associated with HIT post cardiac surgery may assist in patient management prior to obtaining HIT ELISA results.
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