Abstract

T2D disproportionately affects youth of minority and lower SES backgrounds with public insurance. Continuous glucose monitor (CGM) use in youth with T1D and adults with T2D benefits glycemia and quality of life. Use of CGM in youth with T2D has not been sufficiently evaluated. We aimed to determine feasibility of CGM use, measured by % wear time per 2-week period (>75% wear-time as goal) prior to clinic visit, clinical outcomes including time in range (TIR) and HbA1c. Youth were provided or prescribed Libre 2 CGM and followed using established clinic workflows with data collection at each visit. We present the first 6 months (m) of data. We enrolled 30 youth with T2D, mean age 15.1 y and mean HbA1c 10.2% (6.5%-15.5%) (Table 1). At baseline, 37% had history of prior intermittent CGM use and 53% did not have glucometer data. At 3 m 47% of youth who attended visits were using CGM, at 6 m 79% were using CGM, with no participant using CGM >75% of the time. Mean HbA1c was lower over 6 months (1.3% decrease in 8 youth with 6m CGM data and HbA1c) and TIR was lower between 3 and 6 m among those who attended clinic visits. CGM use for 6 m was not sustained in youth with T2D, but CGM was worn by a portion of youth and associated with lower HbA1c in those who used CGM. Strategies for CGM use in youth with T2D may differ from adults with T2D or youth with T1D. Additional studies are needed to evaluate facilitators and barriers of CGM use to optimize CGM use in youth with T2D. Disclosure S.Shah: Research Support; Boehringer-Ingelheim, Takeda Pharmaceutical Co., Ltd. N.Arrizon-ruiz: None. A.Loyola: None. P.Sagan: None. B.P.Conrad: Advisory Panel; Edgepark medical supplies, Consultant; Abbott Diabetes. J.Leverenz: None. F.K.Bishop: None. D.M.Maahs: Advisory Panel; Medtronic, LifeScan Diabetes Institute, MannKind Corporation, Consultant; Abbott, Research Support; Dexcom, Inc. Funding Stanford Diabetes Research Center (P30DK116074)

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