Abstract
To evaluate the relation between calcium intake and bone mineralisation whole body BMC was determined twice (Hologic 1000/W DXA scanner) with one year interval in healthy children aged 5-19 y (F 201, M 142). Calcium intake was measured with a Food Frequency Questionnaire and pubertal stages were assessed ad modum Tanner at the first scan. The association between calcium intake and BMC at the first examination, controlled for bone area, height, weight and age was estimated using multiple regression. Annual bone calcium accretion expressed as mg calcium per day was calculated as the difference between the two DXA scans (data not shown). The ratio between bone calcium accretion rate (mg/d) and calcium intake (mg/d) was calculated. There was a modest but significant effect of calcium intake on BMC. A 100% increase in calcium intake was associated with a 0.8% higher BMC in girls (p=0.04) and a 1.1% higher BMC in boys (p=0.04). Table Conclusion: The results suggest a significant effect of calcium on BMC. The bone calcium retention in relation to calcium intake was highest in mid-puberty indicating a better utilization of calcium in this age group.
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