Abstract
Visual evoked responses (VER) were studied in 10 children with hypothyreoidism. The age when the disease was discovered varied from 1 week to 1½ years. Five infants were younger than 3 months, three between 3 - 6 months. The diagnosis was in all cases verified by the finding of low levels of T3, T4 or PBJ and markedly increased levels of TSH in blood. Nine ohildrenwere examined repeatedly,.7 younger infants were followed up during several months. In all of them EEG responses to photostimulation were recorded. In 4 infants also somatosensory evoked responses (SER) were examined. Before treatment prolonged latencies and/or less mature patterns of VERs were observed. Most increased latencies were found in infants during the first months of age. During hormonal therapy latencies decreased to the normal level (or below it) and followed then the normal developmental curve. Also the response pattern became normal. Photic driving improved very rapidly, SSRs if recorded, behaved in the same way as VERs. The results show, that VERs are useful for assesment of the degree of the delay in the development of the brain and effectivity of the treatment in congenital hypothyreoidism.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
