1075 Assessment and relevance of ventricular wall stress in dilated cardiomyopathy

Abstract

enddiastolic and endsystolic volume (r = 0.73, P < 0.001; r = 0.70, P < 0.001), patients with DCM exhibited increased LV wall stress. Both enddiastolic and endsystolic LV wall stress were correlated with the enddiastolic LV volume (r = 0.54, P < 0.001; r = 0.81, P < 0.001). LV enddiastolic wall stress was correlated with pulmonary pressure (capillary: r = 0.69, P < 0.001; artery: r = 0.67, P 8 kPa: 587 ± 648 pg/ml, P 12 kPa: 715 ± 661 pg/ml, P < 0.001; normal = 4 kPa: 124 ± 203 pg/ml). Analysis of variance revealed LV enddiastolic wall stress as the only independent hemodynamic parameter influencing BNP (P < 0.01). When compared with the CMR based wall stress analysis, the echocardiography based method underestimated LV wall stress systematically.