Abstract

PD-L1 expression is the most implemented biomarker in clinical practice for immunotherapy in NSCLC; however, not all patients benefit from this treatment and PD-L1 testing alone is not yet an adequate biomarker for patient selection. Consequently, new approach is necessary to identify effective biomarkers. The aim of the project is to characterize T cell receptor β chain (TCRβ) repertoire in a cohort of advanced NSCLC patients treated with anti-PD1.

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