1057 Nutritional Deficit Among Extremely Low Birth Weight Infants is Evitable

Abstract

Postnatal malnutrition and growth retardation were shown as inevitable consequence of current recommendations in preterm infants. In 2006, we modified our nutritional guideline: Objectives: To compare energy and protein cumulative deficits over the first seven weeks of life. Method: Optimal energy and protein intakes were set at 120Cal/kg.d and 3g/kg.d respectively and used to calculate positive cumulative deficits. We compared 2 groups of ELBW infants below 28 weeks born in 2005 and 2009 who stayed at least 7 weeks in our unit. Results are reported as median (Q1, Q3). Mann-Whitney tests were performed for each criteria. Results: Groups were not different for GA (p=0.277) and BW (p=0.106). At the end of the 1st and the 7th week, energy and protein deficit were significantly reduced in the 2009 group. Energy (Cal/kg): W1:419(378, 450) versus 375(327, 421), p=0.002; W7: 983(724, 1355) versus 48(-270, 484), p< 0.01 Protein (g/kg): W1: 5.77(5.06, 7.72) versus -0.19(-1.4, 0.65), p< 0.01 ; W7 : 1.14(-6.55, 6.68) versus-18.72(-27, -12.62), p< 0.01. Conclusion: Higher parenteral intakes and close attention to enteral feeding allowed a reduction of nutritional deficit. Nonetheless, potential clinical effect had to be studied.