Abstract
It is generally accepted that the carcinogenic process in mammalian cell systems involves multiple steps that result in distinct phenotypic alterations associated with immortalization, progression, and conversion to malignancy. Prostate cancer, as the most common cancer in men, presents a particular challenge: not all histologic cancer progresses to clinical malignancies. The steps necessary for prostate carcinogenesis need to be defined and model systems expanded. We report the neoplastic transformation of an immortalized human prostate epithelial cell line (267Bl) by ionizing radiation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Radiation Oncology*Biology*Physics
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
