Abstract
Results: In the cohort of 1328 patients, 665 (50%) had low AFP (<20ng/ml), 473 (36%) medium (21–399ng/ml), and 190 (14%) high (≥400ng/ml). In the ITA.LI.CA (no-LT) and in the USA (post-LT) multivariate models, hazard ratios (95% confidence interval) associated with increasing AFP values were 0.94 (0.80– 1.11) and 1.50 (1.19–1.89) for AFP medium vs. low, 1.49 (1.21–1.83) and 2.11 (1.55–2.88) for AFP high vs. low, respectively. Monte Carlo simulation showed the absence of a significant correlation between AFP and transplant benefit, being the median 5-year transplant benefit in months (inter-quartile range) 15.28 (13.26–17.51), 10.65 (7.83–13.30), and 12.49 (9.15–15.99) for AFP low, medium, and high categories respectively. Conclusion: AFP does not predict the survival benefit of LT in HCC patients.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
