Abstract
Background: Breast cancer (BC) is the most commonly diagnosed cancer and the leading cause of cancer-related death among women worldwide. It is a complex, heterogeneous disease in which several lifestyle-related and genetic factors are implicated in its pathogenesis. The phosphatidylinositol 3-kinase (PI3 K) is a complex signaling pathway that plays an essential role in cell growth, proliferation, epithelial to mesenchymal transition, survival, invasion, migration, and apoptosis. It is often altered in BC caused by mutations or amplification of the genes encoding the PI3 K catalytic subunits p110α (PIK3CA).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
