1026 Teen pregnancy: better definition of the unique sociodemographic and adverse outcomes in this vulnerable population

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We set out to better define adverse pregnancy and neonatal outcomes in teen pregnancies. Retrospective analysis of the Centers for Disease Control & Prevention’s Natality Live Birth database (2016-2018). All births to teen patients (< 20 years old) were compared with births to patients aged 20 to 35 years old (control group). Baseline and sociodemographic characteristics, as well as pregnancy, maternal and neonatal outcomes were compared between the two groups using Pearson’s chi-square test with Bonferroni adjustment. Multivariate logistic regression was used to adjust outcomes for potential confounders such as body mass index (BMI), race/ethnicity, pre-gestational diabetes and chronic hypertension. Results were presented as adjusted odds ratios (aOR) with 95% confidence intervals (CI), and statistical significance was set as P value < 0.05. Teen pregnancies comprised 6.1% of the cohort (527,366/8,606,590). Baseline characteristics varied significantly between the two groups, with underweight BMI, non-Hispanic Black race and Hispanic ethnicity being significantly more common in teens (7.3% versus 3.4%; 21.6% versus 14.8%; and 38.2% versus 24%; respectively, p<0.001), (Table 1). Teen pregnancies were also associated with increased odds of several adverse outcomes such as hypertensive disorders of pregnancy (aOR 1.32, 1.33-1.34), eclampsia (aOR 1.53, 1.46-1.61), preterm birth (aOR 1.4, 1.39-1.41), congenital malformations (aOR 1.37, 1.30-1.44), low 5-minute Apgar score (aOR 1.48, 1.45-1.51), and neonatal seizures (aOR 1.45, 1.26-1.67) (Table 2). Additionally, teen pregnancies had lower odds of gestational diabetes, twin gestation, uterine rupture and unplanned hysterectomy (Table 2). Based on this large US population cohort, we better identify significant racial/ethnic disparities in teen pregnancies as well as significant differences in the rates of several adverse pregnancy and neonatal outcomes. Our findings better define the scope of adverse outcomes associated with this vulnerable patient population.View Large Image Figure ViewerDownload Hi-res image Download (PPT)