Abstract
induced mammary gland tumours are cytokeratin 5 (K5) and cytokeratin 6 (K6) positive. Conclusions: Taken together these data indicate that long term low level expression of GLI1 induces formation of mammary gland tumours with a basal character and that GLI1 expression affects the mammary gland stem cells. The orphan GPCR Lgr5 is expressed in the basal cell layer of the large mammary ducts and might include the mammary stem cell population.
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