Abstract
Since most of the Gallbladder carcinoma(GBC) patients present at advanced stage, curative surgery is not feasible and they have high recurrence rate. As surgical resection is curative for GBC, downstaging by neoadjuvant chemotherapy (NACT) like Gemcitabine and Cisplatin may increase the chances of complete resection with no microscopic residual (R0 resection) and thereby improving survival. The present prospective study is being undertaken to assess the response of NACT in locally advanced Gall Bladder cancer(LAGBC) patients and further asses them for surgical resection.
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