1009

Abstract

Introduction: Centrifugal blood pumps are being increasingly used to support adults requiring veno-venous (VV) extracorporeal membrane oxygenation support (ECMO). Hypothesis: Our aim was to determine if survival and ECMO related morbidities between adults undergoing VV ECMO differed by pump type. Methods: Adults > 18 years old who underwent VV ECMO support (n = 1585) during 2005 – 2011 and reported to the ECMO registry of the Extracorporeal Life Support Organization with inclusion of pump identity. Data were limited to VV mode and for those patients who underwent more than 1 run of ECMO, only data from the first run was analyzed (n = 907). Using Greedy 1:1 propensity score matching of pre-ECMO characteristics, we compared ECMO-related outcomes in adults supported with centrifugal versus roller style pumps. Results: A total of 406 patients (203 in per pump type) were included. There were no significant differences in pre-ECMO related variables. Adults supported with centrifugal pumps had increased odds of hemolysis OR=5.4 [95% CI 2.3 – 12.6], however, had a decreased odds of diagnosis of surgical bleeding OR=0.51 [0.28 – 0.93] and diagnosis of pneumothorax OR=0.49 [0.26 – 0.93]. There was no difference in odds of acute renal injury between pump type. Survival did not differ between groups. Conclusions: In a propensity score matched cohort of adult ECMO patients, adults supported with centrifugal pumps had increased odds of hemolysis. However there was no difference in odds of renal injury or survival between pump type.