1008-P: Utility of a Comprehensive Physical Fitness Score by the Tests of Physical Fitness in Screening of Metabolic Diseases

Abstract

A significant number of patients with metabolic diseases, including diabetes, remain undiagnosed worldwide. Although individual components of physical fitness have been shown to be predictive of metabolic diseases, it remains unclear whether a comprehensive assessment by physical fitness tests can be used to screen for metabolic diseases without clinical testing. Thus, we developed a new Physical Score consisting of comprehensive physical fitness indicators and elucidated the association between the resultant Physical Score and metabolic diseases, i.e., diabetes, hypertension, dyslipidemia, fatty liver, and metabolic syndrome, among Japanese. Analyzed were 49,850 persons (30,039 men) aged 30 to 69 y who underwent physical fitness tests. Principal component analysis was performed on the correlation matrix of the physical fitness test results (grip strength, single-leg balance, and trunk flexibility) according to sex and age. We defined the Physical Score as the first principal component score. The mean of the Physical Score was 0±1.1 (min -4.8, max 7.1). Multivariate logistic regression analysis showed that the risk of metabolic diseases increased approximately 1.2-1.4 times per 1 point reduction in the Physical Score (Table). The Physical Score is a useful and simple non-invasive tool for screening Japanese people for metabolic diseases.View largeDownload slideView largeDownload slide DisclosureT. Sato: None. K. Fujihara: None. M. H. Yamada: None. Y. Yaguchi: None. M. Kitazawa: None. M. Yamamoto: None. S. Kodama: None. K. Kato: None. H. Sone: Research Support; Self; Astellas Pharma Inc., Eisai Co., Ltd., Kyowa Kirin Co., Ltd., Novo Nordisk, Ono Pharmaceutical Co., Ltd., Taisho Pharmaceutical Co., Ltd., Takeda Pharmaceutical Co.