100名医学生后极部脉络膜厚度的测量与分析

Abstract

目的：应用增强深部成像的相关光断层扫描(EDI-OCT)仪测量100名医学生后极部脉络膜的厚度，并分析其与性别、眼轴之间的关系。方法：研究对象为100名医学院大学生，平均年龄23.1 ± 1.1岁。应用EDI-OCT扫描受检者双眼后极部脉络膜，分别测量黄斑中心凹下及距离黄斑中心凹3 mm处的脉络膜厚度。结果：黄斑中心凹处脉络膜厚度(SFCT)平均为202.8 ± 49.0 µm。黄斑中心凹上方3 mm处脉络膜厚度最厚，为235.9 ± 68.4 µm。黄斑中心凹鼻侧3 mm处脉络膜最薄为150.5 ± 55.5 µm。男性与女性脉络膜厚度之间的差别以及左右眼之间的差别无明显统计学意义(P > 0.05)。眼轴长度在23.23 mm到27.88 mm范围内，随眼轴长度每增长1 mm，黄斑鼻侧脉络膜厚度减少17.46 µm。其他四个位置的脉络膜厚度无明显规律可循。结论：100名医学生后极部脉络膜的厚度与性别无关，而黄斑中心凹鼻侧脉络膜厚度随眼轴增长有变薄的趋势。 Objective: To study posterior choroidal thickness in 100 medical students and to determine its cor-relation with sex and axial length. Materials and Methods: Cross-sectional observational study of 197 eyes in 100 medical students (mean age = 23.1 ± 1.1 years). The macular choroid was imaged using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). Subfoveal choroidal thickness (SFCT) and choroidal thickness were measured by visual inspection and manual fitting of the choroidal borderlines, at 3 mm inferior, superior, nasal, and temporal to the fovea, respectively. Results: The mean SFCT was 202.8 ± 49.0 µm. The choroidal thickness was the biggest (235.9 ± 68.4 µm) at 3 mm superior to the fovea, and was the thinnest (150.5 ± 55.5 µm) at 3 mm nasal to the fovea. No significant difference had been found in the choroidal thickness between male and female volunteer (P > 0.05), either between right and left eyes (P > 0.05). Ocular axial length between 23.23 mm to 27.88 mm, foveal nasal lateral choroidal thickness decreased by 17.46 µm per mm along axial length, the difference between the other four sites of the choroidal thickness was without obvious regularity. Conclusions: The posterior choroidal thickness of 100 medical students has nothing to do with sex, while the foveal nasal lateral choroidal thickness gets thinner with the axial growth.