Abstract
Background: Over a decade of years, from 1999–2008, guidelines for treatment of patients with myocardial infarction (MI) have been regularly updated and new definitions for acute MI have been established. Aim of the present study was to investigate the changes in treatment and hospital mortality over this 10-year period in acute MI-patients under the influence of the implementation of guideline-based therapy and the redefinition of acute myocardial infarction in Berlin, Germany. Methods: In the BMIR, data of patients with acute myocardial infarction (AMI) have been collected prospectively since 1999. We analyzed data from 1.1.1999–1.4.2008 of 11 hospitals continuously participating in the BMIR. We consecutively included 9830 MI patients. Demographic data, data on reperfusion therapy and discharge medication, and on hospital mortality were analyzed. Results:
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