10 Quality of Live and Muscle Strength in Adults with Low and Moderate to High Risk of Osteoporotic Fracture

Abstract

Abstract Osteoporotic fracture is known contributor to decline quality of life (QoL) and muscle strength. We aimed to examine the association between quality of life and muscle strength in adults at risk of osteoporotic fracture. A cross-sectional study was conducted among 105 adults aged 50 years and above (69.3 ± 8.5 years) at a spine orthopaedic clinic. Upper and lower limb muscle strength were measured using dominant hand grip strength test (HGS) and 5-sit to stand test (5STS). Quality of life and osteoporotic fracture risk were assessed using EQ5DVAS questionnaire and fracture risk calculator (FRAX®). Approximately 38% of the participants had moderate to high risk of major osteoporotic fracture. Although lower, the total mean score of EQ5DVAS in adults with low (80.54 ± 13.20) and moderate to high (76.88 ± 16.90) risk of osteoporotic fracture was not significantly different (p = 0.77). Adults with risk of osteoporotic fracture had slight to severe problems in EQ5D subdomains (mobility: 30%, self-care:10%, usual activities: 14%, pain discomfort: 60%, anxiety/depression: 46%). After adjusting for femoral neck bone mineral density and education level, higher HGS score (ß = 0.79, 95% C.I: 0.07-1.52, p < 0.05) and shorter time to complete 5STS (ß =-1.02, 95% C.I:-1.86 - -0.19, p < 0.05) were associated with higher QoL scores. Our study results suggest that muscle strength is positively associated with QoL among adults at risk of osteoporotic fracture. Muscle strength training should be emphasised among adults with risk of osteoporotic fracture in view of improving QOL.