Abstract
Gastrointestinal (GI) bleeding occurs frequently in patients with a left ventricular assist device (LVAD). Evidence suggests a major role for von Willebrand Factor (vWF). However, a mechanistic link between vWF degradation and GI angiodysplasia has not been explored. We investigated whether LVAD-associated vWF degradation fragments generated by shear stress and ADAMTS-13 (the vWF protease) affected angiogenesis in vitro.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
