Abstract
Common variable immunodeficiency (CVID) is one type of primary immunodeficiency (PID) that is characterized by an impaired ability to produce antibodies, associated with severe and recurrent infections. We report the case of a 31-year-old man who was given a diagnosis of CVID with lack of B cells, decreased neutrophil levels, and disturbed production of T cells. The patient required pulpectomy and third-molar extraction. Although he was receiving prophylactic antibiotic and immunoglobulin replacement therapy at regular intervals to reduce the risk of infection and end-organ damage, we planned to additionally administer an intravenous human immunoglobulin preparation immediately before dental treatment and antibiotics in the perioperative period. Single-visit root canal treatment, immediate filling of the left lower second molar, and extraction of 4 third molars were performed without complications during the perioperative period. There was no severe infection as of 6 months after treatment.
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