Abstract
Mixed connective tissue disease (MCTD) was defined in 1972 by Sharp et al. as a connective tissue disorder characterized by overlapping features of systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS), and high titers of anti U1-ribonucleoprotein (RNP) antibody. In this report, a case of MCTD associated with temporomandibular joint (TMJ) disturbances is described. The patient was a 30-year-old woman who was given a diagnosis of MCTD 7 years previously. At the first visit, the amount of mouth opening was about 24 mm, with jaw opening pain, palpation tenderness of the TMJ and masseter muscle tenderness on both sides. She also had a habit of chewing on one side. MRI revealed deformity of the condyles, bilateral anterior disc displacement without reduction, and related findings. She was treated by conservative methods, including muscle relaxants, massage, jaw-opening training, eliminating bad habits, and a stabilization splint. During treatment, the symptoms improved gradually except for trismus, which continues at present. If it is therefore necessary for her to receive conservative therapy hereafter.
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