Abstract
We describe a rare case of desmoplastic ameloblastoma （DA） arising in the mandible of a 47-year-old man. A round, elastic hard, painless mass, measuring 16 mm in diameter, was detected in the right anterior region of the mandible. The surface of the mass was smooth, and the overlying gingival mucosa was normal. Radiographic examinations showed a honeycomb appearance with ill-defined margins. Immunohistochemically, the expression of TGF-β1 and TGF-βreceptor type I was detected in the tumor cells, suggesting that TGF-β1 might have played an important role in the formation of DA. The mass was completely resected through an intraoral approach under general anesthesia, and the postoperative course has been uneventful for 1 year.
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