1-(4-Nitrophenoxycarbonyl)-7-pyridin-4-yl indolizine: a new versatile fluorescent building block. Application to the synthesis of a series of fluorescent β-cyclodextrins

Abstract

The synthesis of a series of new fluorescent building blocks 1a– d incorporating a pyridinoindolizine unit and two potentially reactive sites is described. The reaction of 1a– d with the mono-6-amino-6-deoxy-β-cyclodextrin provides the corresponding fluorescent water soluble hosts 2a– d in good yield. The sensor properties of 2a– d in the presence of 1-adamantanol is described.