Abstract
A new member of the 2-acetylpyridine family has been prepared and characterized. Its synthesis is a two-step process starting from a pyridyl-alcohol in which the ketone moiety is protected as a cyclic acetal. Alkylation of the alcohol followed by hydrolysis of the acetal afforded the title compound in 52% overall yield.
Highlights
A new member of the 2-acetylpyridine family has been prepared and characterized
Alkylation of the alcohol followed by hydrolysis of the acetal afforded the title compound in 52% overall yield
This paper described the preparation of 1-{4-[(hexyloxy)methyl]pyridin-2-yl}ethanone, which is one member of this 2-acetylpyridine family
Summary
Such compounds have been used as starting materials in the intermediates. 2-Acetylpyridine derivatives are interesting synthetic example, such compounds [1,2,3], of complexes anti-microbial properties [4,5], of pyridinyl-pyrimidines [6],agents of catalysts have been used as with starting materials in the preparation of potential anti-cancer [1,2,3],. [7,8,9], materials for anti-microbial water treatment [10] or molecules possessing magnetic properties [11] just to of complexes with properties [6], of catalysts [7,8,9], name a few.
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