Abstract
1,4-Diazabicyclo[2.2.2]octane (DABCO)-mediated ring opening of 1-acetylcyclopropanecarboxamides efficiently gave stable zwitterions that could be formed <i>in situ</i> or readily isolated. An application of this novel type of ring opening was demonstrated in a one-pot efficient construction of biologically interesting 3-alkyl γ-lactams. The Lewis-base protocol provides an opportunity for performing ring opening, cycloaddition, and rearrangement reactions of donor–acceptor cyclopropanes through organocatalysis.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
