Abstract
Thermolysis of 4-alkoxy-l,3-oxazol-5(2H)-ones (2) (X = O) leads to reactive nitrile ylides (1) bearing an alkoxy substituent at the nitrile C-atom. These intermediates can be trapped by C,C-, C,O-, C,N-, and C,S-dipolarophiles, yielding 5-membered heterocycles via 1,3- dipolar cycloaddition. In the case of 1,3-thiazole-5(4H)-thiones (11) as dipolarophiles, two regioisomeric cycloadducts were obtained. The results of the cycloadditions are discussed with respect to the influence of the alkoxy substituent on the structure of the nitrile ylide.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
