Abstract
The two isomers 1,2,3,5,6,7- and 1,2,3,4,6,7-hexachloronaphthalene are shown to be selectively retained in the liver of rats orally dosed with the commercial PCN product Halowax 1014. The retention was further studied by dosing rats orally with a mixture of the two compounds. The rats were sacrificed after 1, 10, 35 and 120 days, respectively. The two hexachloronaphthalenes were found to be strongly retained in the liver and the concentration ratios liver/adipose tissue were remarkably high. 1,2,3,5,6,7- And 1,2,3,4,6,7-hexachloronaphthalene were also found to be present in two environmental samples from the Swedish east coast, cod liver and guillemot egg.
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