Abstract

1,1,2,2,3,3,4,4,4-Nonafluorobutane-1-sulfonyl fluoride (NfF) is a versatile compound in organic synthesis. It can be used as a fluoride source for the nucleophilic introduction of fluorine,[1] but it is also frequently applied as sulfonylation reagent generating intermediates with strong electron-withdrawing perfluorinated alkyl substituents.[2]

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