Abstract
Active soluble Fas ligand (sFasL) accumulates in lung fluid of patients with acute respiratory distress syndrome (ARDS), and causes apoptosis and inflammation in lung epithelial cells [1]. Alveolar epithelial damage induced by Fas receptor activation results in protein-rich lung edema [2]. Dysfunction of the tight junction proteins may contribute to the formation of lung edema.
Highlights
Active soluble Fas ligand accumulates in lung fluid of patients with acute respiratory distress syndrome (ARDS), and causes apoptosis and inflammation in lung epithelial cells [1]
Alveolar epithelial damage induced by Fas receptor activation results in protein-rich lung edema [2]
Dysfunction of the tight junction proteins may contribute to the formation of lung edema
Summary
Determine whether sFasL increases protein permeability of the alveolar epithelium by mechanisms involving disruption of the tight junction proteins in ARDS.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
