Abstract

Darier disease and Hailey-Hailey disease are severe, monogenetic dermatological disorders with mutations affecting all cells, making them liable to exhibit extra-dermal symptoms. The purpose of this study is to assess broad cognitive function in individuals with both diseases using an experimental, case-control setup comparing cognition in patients compared with healthy controls matched for age, sex and level of education. Cognition was assessed with the Cambridge Neuropsychological Test Automated Battery.

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