0877 SLEEP AND PARKINSON’S DISEASE: PREVALENCE IN AN OUTPATIENT MEXICAN CLINIC

Abstract

Abstract Introduction Sleep disturbance in patients with Parkinson's disease (PD) is highly prevalent. PD is the second most common progressive neurodegenerative disease, affecting about 1% of people over 60 years. Little it's said about the sleep disorders in this disease, which are very frequent and frequently underdiagnosed. In Mexico, there are not a lot of studies on PD and sleep disorders in their population. University Hospital Dr. José E. González having the only Parkinsons' clinic in the northeast of Mexico for the population without medical coverage, has recognized the importance of unreported sleep disorders in their broad patient population. Methods Patients of the outpatient clinic whom their medical query wasn’t about sleeping disorder were screened using the following clinical tools: the Pittsburgh Sleep Quality Index (PSQI), the Patient Health Questionnaire (PHQ-9), the STOP-BANG Questionnaire, and the Epworth Scale. A full clinical history was also taken, focusing on sleep habits and risk factors that could contribute to sleep difficulties. Results A total of 65 patients (26 females, 39 males) that attended the outpatient Parkinson’s clinic were screened for sleep disorders. Fifty-nine patients (90.7%) were identified with at least 3 risk factors for obstructive sleep apnoea with the STOP-BANG questionnaire and were ordered polysomnography. Using the PSQI we identified 56 patients (86.1%) with low-quality sleep (defined as a score of 5 or higher). With the PHQ-9 we identified 41 patients (63%) with a high risk of depression, none of them were receiving treatment. And the Epworth Scale helped us identify 33 patients (50%) with a possible pathological excessive daytime sleepiness, none of them diagnosed. Conclusion PD is associated with multiple sleep disorders, which commonly impair quality of life. Routine inquiry about sleep problems from healthcare providers can increase its detection in a clinical setting outside of a sleep clinic and better management. Further research should focus on improving screening and diagnostic tools in the PD population. With this initiative, we present our experience and results incorporating routine screening for these disorders, future exploration toward this direction may hopefully shed light on developing effective, mechanisms-driven treatment options. Support (if any)