Abstract
Analogous to DNA and histone modifications, RNA molecules are chemically modified, the study of which gives rise to the field called epitranscriptomics. Among these modifications, N6-methyladenosine (m6A) RNA methylation is the most abundant internal modification in messenger RNA (mRNA) and non-coding RNA in eukaryotic cells, which regulates RNA metabolism, including RNA decay, translation and nuclear processing. However, the regulatory and functional role of m6A RNA methylation in skin cancer remain poorly understood.
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